Ancient Greek View on Olive Oil as Part of the Healthy Mediterranean Diet

“I may instance olive oil, which is mischievous to all plants, and generally most injurious to the hair of every animal with the exception of man, but beneficial to human hair and to the human body generally; and even in this application (so various and changeable is the nature of the benefit), that which is the greatest good to the outward parts of a man, is a very great evil to his inward parts: and for this reason physicians always forbid their patients the use of oil in their food, except in very small quantities, just enough to extinguish the disagreeable sensation of smell in meats and sauces.
~Socrates dialogue with Protagoras

So what did ancient Greeks most often use for cooking? They preferred animal fat, most likely lard. Pigs have a much higher amount of fat than most other animals. And pigs are easy to raise under almost any conditions: cold and hot, fields and forests, plains and mountains, mainlands and islands. Because of this, lard is one of the few common features in many traditional societies, including the longest-lived populations.

That was true of the ancient Greeks, but it has been true ever since in many parts of the world, especially in Europe but also in Asia. This continued to be true as the Western world expanded with colonialism and new societies formed. As Nina Teicholz notes, “saturated fats of every kind were consumed in great quantities. Americans in the nineteenth century ate four to five times more butter than we do today, and at least six times more lard” (The Big Fat Surprise).

To return to the Greeks, the modern population is not following a traditional diet. Prior to the World War era, pork and lard was abundant in the diet. But during wartime, the pig population was decimated from violence, disruption of the food system, and the confiscation of pigs to feed the military.

The same thing happened in the the most pig-obsessed culture in history, the long-lived Okinawans, when the Japanese during WWII stole or killed all of their pigs — as the Japanese perceived these shamanistic rural people on an isolated island to be a separate race and so were treated as less worthy. The Okinawans independence was dependent on their raising pigs and that was taken away from them.

When Greeks, specifically Ikarians, and Okinawans were studied after the war, the diet observed was not the diet that existed earlier, the traditional lard-based and nutrient-dense diet that most of the population had spent most of their lives eating. They were long-lived not because of the lack of lard but because of it once having been abundant.

In various videos about Blue Zones, some Ikarians were interviewed. One centenarian said that when asked his favorite food, he said it was pork; and the response was that is the worst meat. He then explained that, if pork were that bad, then I wouldn’t be here talking to you. Another Ikarian pointed out that every year researchers would ask him about his diet, but no one had bothered to ask him what he cooked with, which was lard.

So, something like olive oil, once primarily used as a lamp fuel, was turned to in replacing the lost access to lard. Olive oil was maybe more of a poverty food used out of necessity, not out of preference. Or else it simply was scarce in the diet because it was otherwise a much needed commodity for other non-dietary purposes. Keep in mind that electricity is a recent introduction to the Greek island Ikaria, one of the Blue Zones Dan Buettner visited.

About that population, Vice put out a video in 2021: The Tiny Island in Greece With the Oldest Life Expectancy in the World. The first Ikarian mentioned was 76 years old and so he would’ve been born in the mid-1940s. This guy stated that, when he was born, Ikaria still did not have electricity. That means they were probably still primarily using olive oil for lamp fuel and not in their diet.

The combination of the pigs being decimated during WWII and electricity replacing lamps suddenly made olive oil available and necessary in the diet. But all of the centenarians studied were born, grew up, and spent their early adulthood prior to WWII and electricity. They would’ve been reliant on lard, particularly in Ikaria where they were an isolated island community at the time.

It is great credit to modern marketing and propaganda that olive oil has been sold as a healthy oil when, in fact, most olive oil bought in the store is rancid. Olive oil is actually a fruit juice which is why it can’t be kept long before going bad, maybe why it gained a bad reputation in ancient Greece and wasn’t commonly used until the post-war era.

Lard and other animal fats, on the other hand, because they are heavily saturated have long shelf-life and don’t oxidize when used for cooking. Also, unlike vegetable oils, animal fats from pastured animals is filled with fat-soluble vitamins and omega-3 fatty acids, essential to health and longevity. How did this traditional knowledge, going back to the ancient world, get lost in a single generation of devastating war?

* * *

American Heart Association’s “Fat and Cholesterol Counter” (1991)

Even hydrogenated fat gets blamed on saturated fat, since the hydrogenation process turns some small portion of it saturated, which ignores the heavy damage and inflammatory response caused by the oxidization process (both in the industrial processing and in cooking). Not to mention those hydrogenated fats as industrial seed oils are filled with omega-6 fatty acids, the main reason they are so inflammatory. Saturated fat, on the other hand, is not inflammatory at all. This obsession with saturated fat is so strange. It never made any sense from a scientific perspective. When the obesity epidemic began and all that went with it, the consumption of saturated fat by Americans had been steadily dropping for decades, ever since the invention of industrial seed oils in the late 1800s and the fear about meat caused by Upton Sinclair’s muckraking journalism, The Jungle, about the meatpacking industry.

The amount of saturated fat and red meat has declined over the past century, to be replaced with those industrial seed oils and lean white meat, along with fruits and vegetables — all of which have been increasing.** Chicken, in particular, replaced beef and what stands out about chicken is that, like those industrial seed oils, it is high in the inflammatory omega-6 fatty acids. How could saturated fat be causing the greater rates of heart disease and such when people were eating less of it. This scapegoating wasn’t only unscientific but blatantly irrational. All of this info was known way back when Ancel Keys went on his anti-fat crusade (The Creed of Ancel Keys). It wasn’t a secret. And it required cherrypicked data and convoluted rationalizations to explain away.

Worse than removing saturated fat when it’s not a health risk is the fact that it is actually an essential nutrient for health: “How much total saturated do we need? During the 1970s, researchers from Canada found that animals fed rapeseed oil and canola oil developed heart lesions. This problem was corrected when they added saturated fat to the animals diets. On the basis of this and other research, they ultimately determined that the diet should contain at least 25 percent of fat as saturated fat. Among the food fats that they tested, the one found to have the best proportion of saturated fat was lard, the very fat we are told to avoid under all circumstances!” (Millie Barnes, The Importance of Saturated Fats for Biological Functions).

It is specifically lard that has been most removed from the diet, and this is significant as lard was a central to the American diet until this past century: “Pre-1936 shortening is comprised mainly of lard while afterward, partially hydrogenated oils came to be the major ingredient” (Nina Teicholz, The Big Fat Surprise, p. 95); “Americans in the nineteenth century ate four to five times more butter than we do today, and at least six times more lard” (p. 126). And what about the Mediterranean people who supposedly are so healthy because of their love of olive oil? “Indeed, in historical accounts going back to antiquity, the fat more commonly used in cooking in the Mediterranean, among peasants and the elite alike, was lard.” (p. 217).

Jason Prall notes that long-lived populations ate “lots of meat” and specifically, “They all ate pig. I think pork was the was the only common animal that we saw in the places that we went” (Longevity Diet & Lifestyle Caught On Camera w/ Jason Prall). The infamous long-lived Okinawans also partake in everything from pigs, such that their entire culture and religion was centered around pigs (Blue Zones Dietary Myth). Lard, in case you didn’t know, comes from pigs. Pork and lard is found in so many diets for the simple reason pigs can live in diverse environments, from mountainous forests to tangled swamps to open fields, and they are a food source available year round.

Blue Zones Dietary Myth

And one of the animal foods so often overlooked is lard: “In the West, the famous Roseto Penssylvanians also were great consumers of red meat and saturated fat. Like traditional Mediterraneans, they ate more lard than olive oil (olive oil was too expensive for everyday cooking and too much in demand for other uses: fuel, salves, etc). Among long-lived societies, one of the few commonalities was lard, as pigs are adaptable creatures that can be raised almost anywhere” (Eat Beef and Bacon!). […]

Looking back at their traditional diet, Okinawans have not consumed many grains, added sugars, industrial vegetable oils, or highly processed foods and they still eat less rice than other Japanese: “Before 1949 the Okinawans ate NO Wheat and little rice” (Julianne Taylor, The Okinawan secret to health and longevity – no wheat?). Also, similar to the Mediterranean people (another population studied after the devastation of WWII) who didn’t use much olive oil until recently, Okinawans traditionally cooked everything in lard that would have come from nutrient-dense pigs, the fat being filled with omega-3s and fat-soluble vitamins. Also, consider that most of the fat in lard is monounsaturated, the same kind of fat that is deemed healthy in olive oil.

“According to gerontologist Kazuhiko Taira, the most common cooking fat used traditionally in Okanawa is a monounsaturated fat-lard. Although often called a “saturated fat,” lard is 50 percent monounsaturated fat (including small amounts of health-producing antimicrobial palmitoleic acid), 40 percent saturated fat and 10 percent polyunsaturated. Taira also reports that healthy and vigorous Okinawans eat 100 grams each of pork and fish each day [7]” (Wikipedia, Longevity in Okinawa).

It’s not only the fat, though. As with most traditional populations, Okinawans ate all parts of the animal, including the nutritious organ meat (and the skin, ears, eyes, brains, etc). By the way, besides pork, they also ate goat meat. There would have been a health benefit from their eating some of their meat raw (e.g., goat) or fermented (e.g., fish), as some nutrients are destroyed in cooking. The small amounts of soy that Okinawans ate in the past was mostly tofu fermented for several months, and fermentation is one of those healthy preparation techniques widely used in traditional societies. They do eat some unfermented tofu as well, but I’d point out that it typically is fried in lard or used to be. […]

The most popular form of pork in the early 1900s was tonkatsu, by the way originally fried in animal fat according to an 1895 cookbook (butter according to that recipe but probably lard before that early period of Westernization). “Several dedicated tonkatsu restaurants cropped up around the 1920s to ’40s, with even more opening in the ’50s and ’60s, after World War II — the big boom period for tonkatsu. […] During the Great Depression of the 1930s, a piece of tonkatsu, which could be bought freshly cooked from the butcher, became the ultimate affordable payday treat for the poor working class. The position of tonkatsu as everyman food was firmly established.” This pork-heavy diet was what most Japanese were eating prior to World War II, but it wouldn’t survive the conflict when food deprivation came to afflict the population long afterwards.

Comment by gp

I just finished reading The Blue Zones and enjoyed it very much, but I was wondering about something that was not addressed in great detail. All of the diets discussed other than the Adventists (Sardinia, Okinawa and Nicoya) include lard, which I understand is actually used in significant quantities in some or all of those places. You describe (Nicoyan) Don Faustino getting multiple 2-liter bottles filled with lard at the market. Does he do this every week, and if so, what is he using all of that lard for? In Nicoya and Sardinia, eggs and dairy appear to play a large role in the daily diet. Your quote from Philip Wagner indicates that the Nicoyans were eating eggs three times a day (sometimes fried in lard), in addition to some kind of milk curd.

The Blue Zones Solutions by Dan Buettner
by Julia Ross (another version on the author’s website)

As in The Blue Zones, his earlier paean to the world’s traditional diets and lifestyles, author Buettner’s new book begins with detailed descriptions of centenarians preparing their indigenous cuisines. He finishes off these introductory tales with a description of a regional Costa Rican diet filled with eggs, cheese, meat and lard, which he dubs “the best longevity diet in the world.”

Then Buettner turns to how we’re to adapt this, and his other model eating practices, into our current lives. At this point he suddenly presents us with a twenty-first century pesco-vegan regimen that is the opposite of the traditional food intake that he has just described in loving detail. He wants us to fast every twenty-four hours by eating only during an eight-hour period each day. He wants us to eat almost no meat, poultry, eggs or dairy products at any time. Aside from small amounts of olive oil, added fats are not even mentioned, except to be warned against.

How Much Soy Do Okinawans Eat?
by Kaayla Daniel

There are other credibility problems with the Okinawa Centenarian Study, at least as interpreted in the author’s popular books. In 2001, Dr. Suzuki reported in the Asia Pacific Journal of Clinical Nutrition that “monounsaturates” were the principal fatty acids in the Okinawan diet. In the popular books, this was translated into a recommendation for canola oil, a genetically modified version of rapeseed oil developed in Canada that could not possibly have become a staple of anyone’s diet before the 1980s. According to gerontologist Kazuhiko Taira, the most common cooking fat used traditionally in Okanawa is a very different monounsaturated fat-lard. Although often called a “saturated fat,” lard is 50 percent monounsaturated fat (including small amounts of health-producing antimicrobial palmitoleic acid), 40 percent saturated fat and 10 percent polyunsaturated. Taira also reports that healthy and vigorous Okinawans eat 100 grams each of pork and fish each day. Thus, the diet of the long-lived Okinawans is actually very different from the kind of soy-rich vegan diet that Robbins recommends.

Nourishing Diets:
How Paleo, Ancestral and Traditional Peoples Really Ate

by Sally Fallon Morell
pp. 263-270
(a version of the following can be found here)

From another source, 7 we learn that:

Traditional foods of Okinawa are extremely varied, remarkably nutrient-dense as are all traditional foods and strictly moderated with the philosophy of hara hachi bu [eat until you are 80 percent full]. While the diet of Okinawa is, indeed, plant-based it is most certainly not “low fat” as has been posited by some writer-researchers about the native foods of Okinawa. Indeed, all those stir fries of bitter melon and fresh vegetables found in Okinawan bowls are fried in lard and seasoned with sesame oil. I remember fondly that a slab of salt pork graced every bowl of udon I slurped up while living on the island. Pig fat is not, as you can imagine, a low-fat food yet the Okinawans are fond of it. Much of the fat consumed is pastured as pigs are commonly raised at home in the gardens of Okinawan homes. Pork and lard, like avocado and olive oil, are a remarkably good source of monounsaturated fatty acid and, if that pig roots around on sunny days, it is also a remarkably good source of vitamin D.

The diet of Okinawa also includes considerably more animal products and meat—usually in the form of pork—than that of the mainland Japanese or even the Chinese. Goat and chicken play a lesser, but still important, role in Okinawan cuisine. Okinawans average about 100 grams or one modest portion of meat per person per day. Animal foods are important on Okinawa and, like all food, play a role in the population’s general health, well-being and longevity. Fish plays an important role in the cooking of Okinawa as well. Seafoods eaten are various and numerous—with Okinawans averaging about 200 grams of fish per day.

Buettner implies that the Okinawans do not eat much fish, but in fact, they eat quite a lot, just not as much as Japanese mainlanders.

The Okinawan diet became a subject of interest after the publication of a 1996 article in Health Magazine about the work of gerontologist Kazuhiko Taira, 8 who described the Okinawan diet as “very healthy—and very, very greasy.” The whole pig is eaten, he noted, everything from “tails to nails.” Local menus offer boiled pig’s feet, entrail soup and shredded ears. Pork is marinated in a mixture of soy sauce, ginger, kelp and small amounts of sugar, then sliced or chopped for stir-fry dishes. Okinawans eat about 100 grams of meat per day—compared to 70 grams in Japan and just over 20 grams in China—and at least an equal amount of fish, for a total of about 200 grams per day, compared to 280 grams per person per day of meat and fish in America. Lard—not vegetable oil—is used in cooking. […]

What’s clear is that the real Okinawan longevity diet is an embarrassment to modern diet gurus. The diet was and is greasy and good, with the largest proportion of calories coming from pork and pork fat, and many additional calories from fish; those who reach old age eat more animal protein and fat than those who don’t. Maybe that’s what gives the Okinawans the attitudes that Buettner so admires, “an affable smugness” that makes it easy to “enjoy today’s simple pleasures.”

Hara Hachi Bu: Lessons from Okinawa
by Jenny McGruther

Traditional foods of Okinawa are extremely varied, remarkably nutrient-dense as are all traditional foods and strictly moderated with the philosophy of hara hachi bu. While the diet of Okinawa is, indeed, plant-based it is most certainly not “low fat” as has been posited by some writer-researchers about the native foods of Okinawa. Indeed, all those stirfries of bittermelon and fresh vegetables found in Okinawan bowls are fried in lard and seasoned with sesame oil. I remember fondly that a slab of salt pork graced every bowl of udon I slurped up while living on the island. Pig fat is not, as you can imagine, a low-fat food yet the Okinawans are fond of it. Much of the fat consumed is pastured as pigs are commonly raised at home in the gardens of Okinawan homes. Pork and lard, like avocado and olive oil, are a remarkably good source of monounsaturated fatty acid and, if that pig roots around on sunny days, it is also a remarkably source of vitamin D.

Carcinogenic Grains

In understanding human health, we have to look at all factors as a package deal. Our gut-brain is a system, as is our entire mind-body. Our relationships, lifestyle, the environment around us — all of it is inseparable. This is true even if we limit ourselves to diet alone. It’s not simply calories in/calories out, macronutrient ratios, or anything else along these lines. It is the specific foods eaten in combination with which other foods and in the context of stress, toxins, epigenetic inheritance, gut health, and so much else that determine what effects manifest in the individual.

There are numerous examples of this. But I’ll stick to a simple one, which involves several factors and the relationship between them. First, red meat is associated with cancer and heart disease. Yet causation is hard to prove, as red meat consumption is associated with many other foods in the standard American diet, such as added sugars and vegetable oils in processed foods. The association might be based on confounding factors that are culture-specific, which can explain why we find societies with heavy meat consumption and little cancer.

So, what else might be involved? We have to consider what red meat is being eaten with, at least in the standard American diet that is used as a control in most research. There is, of course, the added sugars and vegetable oils — they are seriously bad for health and may explain much of the confusion. Saturated fat intake has been dropping since the early 1900s and, in its place, there has been a steady rise in the use of vegetable oils; we now know that highly heated and hydrogenated vegetable oils do severe damage. Also, some of the original research that blamed saturated fat, when re-analyzed, found that sugar was the stronger correlation to heart disease.

Saturated fat, as with cholesterol, had been wrongly accused. This misunderstanding has, over multiple generations at this point, led to the early death of at least hundreds of millions of people worldwide, as dozens of the wealthiest and most powerful countries enforced this in their official dietary recommendations which transformed the world’s food system. Similar to eggs, red meat became the fall guy.

Such things as heart disease are related to obesity, and conventional wisdom tells us that fat makes us fat. Is that true? Not exactly or directly. I was amused to discover that a scientific report commissioned by the British government in 1846 (Experimental Researches on the Food of Animals, and the Fattening of Cattle: With Remarks on the Food of Man. Based Upon Experiments Undertaken by Order of the British Government by Robert Dundas Thomson) concluded that “The present experiments seem to demonstrate that the fat of animals cannot be produced from the oil of the food” — fat doesn’t make people fat, and that low-carb meat-eating populations tend to be slim has been observed for centuries.

So, in most cases, what does cause fat accumulation? It is only fat combined with plenty of carbs and sugar that is guaranteed to make us fat, that is to say fat in the presence of glucose in that the two compete as a fuel source.

Think about what an American meal with red meat looks like. A plate might have a steak with some rolls or slices of bread, combined with a potato and maybe some starchy ‘vegetables’ like corn, peas, or lima beans. Or there will be a hamburger with a bun, a side of fries, and a large sugary drink (‘diet’ drinks are no better, as we now know artificial sweeteners fool the body and so are just as likely to make you fat and diabetic). What is the common factor, red meat combined with wheat or some other grain, as part of a diet drenched in carbs and sugar (and all of it cooked or slathered in vegetable oils).

Most Americans have a far greater total intake of carbs, sugar, and vegetable oils than red meat and saturated fat. The preferred meat of Americans these days is chicken with fish also being popular. Why does red meat and saturated fat continue to be blamed for the worsening rates of heart disease and metabolic disease? It’s simply not rational, based on the established facts in the field of diet and nutrition. That isn’t to claim that too much red meat couldn’t be problematic. It depends on the total diet. Also, Americans have the habit of grilling their red meat and grilling increases carcinogens, which could be avoided by not charring one’s meat, but that equally applies to not burning (or frying) anything one eats, including white meat and plant foods. In terms of this one factor, you’d be better off eating beef roasted with vegetables than to go with a plant-based meal that included foods like french fries, fried okra, grilled vegetable shish kabobs, etc.

Considering all of that, what exactly is the cause of cancer that keeps showing up in epidemiological studies? Sarah Ballantyne has some good answers to that (see quoted passage below). It’s not so much about red meat itself as it is about what red meat is eaten with. The crux of the matter is that Americans eat more starchy carbs, mostly refined flour, than they do vegetables. What Ballantyne explains is that two of the potential causes of cancer associated with red meat only occur in a diet deficient in vegetables and abundant in grains. It is the total diet as seen in the American population that is the cause of high rates of cancer.

As a heavy meat diet without grains is not problematic, a heavy carb diet without grains is also not necessarily problematic. Some of the healthiest populations eat lots of carbs like sweet potatoes, but you won’t find any healthy population that eats as many grains as do Americans. There are many issues with grains considered in isolation (read the work of David Perlmutter or any number of writers on the paleo diet), but grains combined with certain other foods in particular can contribute to health concerns.

Then again, some of this is about proportion. For most of the time of agriculture, humans ate small amounts of grains as an occasional food. Grains tended to be stored for hard times or for trade or else turned into alcohol to be mixed with water from unclean sources. The shift to large amounts of grains made into refined flour is an evolutionarily unique dilemma our bodies aren’t designed to handle. The first accounts of white bread are found in texts from slightly over two millennia ago and most Westerners couldn’t afford white bread until the past few centuries when industrialized milling began. Before that, people tended to eat foods that were available and didn’t mix them as much (e.g., eat fruits and vegetables in season). Hamburgers were invented only about a century ago. The constant combining of red meat and grains is not something we are adapted for. That harm to our health results maybe shouldn’t surprise us.

Red meat can be a net loss to health or a net gain. It depends not on the red meat, but what is and isn’t eaten with it. Other factors matter as well. Health can’t be limited to a list of dos and don’ts, even if such lists have their place in the context of more detailed knowledge and understanding. The simplest solution is to eat as most humans ate for hundreds of thousands of years, and more than anything else that means avoiding grains. Even without red meat, many people have difficulties with grains.

Let’s return to the context of evolution. Hominids have been eating fatty red meat for millions of years (early humans having prized red meat from blubbery megafauna until their mass extinction), and yet meat-eating hunter-gatherers rarely get cancer, heart disease, or any of the other modern ailments. How long ago was it when the first humans ate grains? About 12 thousand years ago. Most humans on the planet never touched a grain until the past few millennia. And fewer still included grains with almost every snack and meal until the past few generations. So, what is this insanity of government dietary recommendations putting grains as the base of the food pyramid? Those grains are feeding the cancerous microbes, and doing much else that is harmful.

In conclusion, is red meat bad for human health? It depends. Red meat that is charred or heavily processed combined with wheat and other carbs, lots of sugar and vegetable oils, and few nutritious vegetables, well, that would be a shitty diet that will inevitably lead to horrible health consequences. Then again, the exact same diet minus the red meat would still be a recipe for disease and early death. Yet under other conditions, red meat can be part of a healthy diet. Even a ton of pasture-raised red meat (with plenty of nutrient-dense organ meats) combined with an equal amount of organic vegetables (grown on healthy soil, bought locally, and eaten in season), in exclusion of grains especially refined flour and with limited intake of all the other crap, that would be one of the healthiest diets you could eat.

On the other hand, if you are addicted to grains as many are and can’t imagine a world without them, you would be wise to avoid red meat entirely. Assuming you have any concerns about cancer, you should choose one or the other but not both. I would note, though, that there are many other reasons to avoid grains while there are no other known reasons to avoid red meat, at least for serious health concerns, although some people exclude red meat for other reasons such as digestion issues. The point is that whether or not you eat red meat is a personal choice (based on taste, ethics, etc), not so much a health choice, as long as we separate out grains. That is all we can say for certain based on present scientific knowledge.

* * *

We’ve known about this for years now. Isn’t it interesting that no major health organization, scientific institution, corporate news outlet, or government agency has ever warned the public about the risk factors of carcinogenic grains? Instead, we get major propaganda campaigns to eat more grains because that is where the profit is for big ag, big food, and big oil (that makes farm chemicals and transports the products of big ag and big food). How convenient! It’s nice to know that corporate profit is more important than public health.

But keep listening to those who tell you that cows are destroying the world, even though there are fewer cows in North America than there once were buffalo. Yeah, monocultural GMO crops immersed in deadly chemicals that destroy soil and deplete nutrients are going to save us, not traditional grazing land that existed for hundreds of millions of years. So, sure, we could go on producing massive yields of grains in a utopian fantasy beloved by technocrats and plutocrats that further disconnects us from the natural world and our evolutionary origins, an industrial food system dependent on turning the whole world into endless monocrops denatured of all other life, making entire regions into ecological deserts that push us further into mass extinction. Or we could return to traditional ways of farming and living with a more traditional diet largely of animal foods (meat, fish, eggs, dairy, etc) balanced with an equal amount of vegetables, the original hunter-gatherer diet.

Our personal health is important. And it is intimately tied to the health of the earth. Civilization as we know it was built on grains. That wasn’t necessarily a problem when grains were a small part of the diet and populations were small. But is it still a sustainable socioeconomic system as part of a healthy ecological system? No, it isn’t. So why do we continue to do more of the same that caused our problems in the hope that it will solve our problems? As we think about how different parts of our diet work together to create conditions of disease or health, we need to begin thinking this way about our entire world.

* * *

Paleo Principles
by Sarah Ballantyne

While this often gets framed as an argument for going vegetarian or vegan. It’s actually a reflection of the importance of eating plenty of plant foods along with meat. When we take a closer look at these studies, we see something extraordinarily interesting: the link between meat and cancer tends to disappear once the studies adjust for vegetable intake. Even more exciting, when we examine the mechanistic links between meat and cancer, it turns out that many of the harmful (yes, legitimately harmful!) compounds of meat are counteracted by protective compounds in plant foods.

One major mechanism linking meat to cancer involves heme, the iron-containing compound that gives red meat its color (in contrast to the nonheme iron found in plant foods). Where heme becomes a problem is in the gut: the cells lining the digestive tract (enterocytes) metabolize it into cytotoxic compounds (meaning toxic to living cells), which can then damage the gut barrier (specifically the colonic mucosa; see page 67), cause cell proliferation, and increase fecal water toxicity—all of which raise cancer risk. Yikes! In fact, part of the reason red meat is linked with cancer far more often than with white meat could be due to their differences in heme content; white meat (poultry and fish) contains much, much less.

Here’s where vegetables come to the rescue! Chlorophyll, the pigment in plants that makes them green, has a molecular structure that’s very similar to heme. As a result, chlorophyll can block the metabolism of heme in the intestinal tract and prevent those toxic metabolites from forming. Instead of turning into harmful by-products, heme ends up being metabolized into inert compounds that are no longer toxic or damaging to the colon. Animal studies have demonstrated this effect in action: one study on rats showed that supplementing a heme-rich diet with chlorophyll (in the form of spinach) completely suppressed the pro-cancer effects of heme. All the more reason to eat a salad with your steak.

Another mechanism involves L-carnitine, an amino acid that’s particularly abundant in red meat (another candidate for why red meat seems to disproportionately increase cancer risk compared to other meats). When we consume L-carnitine, our intestinal bacteria metabolize it into a compound called trimethylamine (TMA). From there, the TMA enters the bloodstream and gets oxydized by the liver into yet another compound, trimethylamine-N-oxide (TMAO). This is the one we need to pay attention to!

TMAO has been strongly linked to cancer and heart disease, possibly due to promoting inflammation and altering cholesterol transport. Having high levels of it in the bloodstream could be a major risk factor for some chronic diseases. So is this the nail in the coffin for meat eaters?

Not so fast! An important study on this topic published in 2013 in Nature Medicine sheds light on what’s really going on. This paper had quite a few components, but one of the most interesting has to do with gut bacteria. Basically, it turns out that the bacteria group Prevotella is a key mediator between L-carnitine consumption and having high TMAO levels in our blood. In this study, the researchers found that participants with gut microbiomes dominated by Prevotella produced the most TMA (and therefore TMAO, after it reached the liver) from the L-carnitine they ate. Those with microbiomes high in Bacteroides rather than Prevotella saw dramatically less conversion to TMA and TMAO.

Guess what Prevotella loves to snack on? Grains! It just so happens that people with high Prevotella levels, tend to be those who eat grain-based diets (especially whole grain), since this bacterial group specializes in fermenting the type of polysaccharides abundant in grain products. (For instance, we see extremely high levels of Prevotella in populations in rural Africa that rely on cereals like millet and sorghum.) At the same time, Prevotella doesn’t seem to be associated with a high intake of non-grain plant sources, such as fruit and vegetables.

So is it really the red meat that’s a problem . . . or is it the meat in the context of a grain-rich diet? Based on the evidence we have so far, it seems that grains (and the bacteria that love to eat them) are a mandatory part of the L-carnitine-to-TMAO pathway. Ditch the grains, embrace veggies, and our gut will become a more hospitable place for red meat!

* * *

Georgia Ede has a detailed article about the claim of meat causing cancer. In it, she provides several useful summaries of and quotes from the scientific literature.

WHO Says Meat Causes Cancer?

In November 2013, 23 cancer experts from eight countries gathered in Norway to examine the science related to colon cancer and red/processed meat. They concluded:

“…the interactions between meat, gut and health outcomes such as CRC [colorectal cancer] are very complex and are not clearly pointing in one direction….Epidemiological and mechanistic data on associations between red and processed meat intake and CRC are inconsistent and underlying mechanisms are unclear…Better biomarkers of meat intake and of cancer occurrence and updated food composition databases are required for future studies.” 1) To read the full report: http://www.ncbi.nlm.nih.gov/pubmed/24769880 [open access]

Translation: we don’t know if meat causes colorectal cancer. Now THAT is a responsible, honest, scientific conclusion.

How the WHO?

How could the WHO have come to such a different conclusion than this recent international gathering of cancer scientists? As you will see for yourself in my analysis below, the WHO made the following irresponsible decisions:

  1. The WHO cherry-picked studies that supported its anti-meat conclusions, ignoring those that showed either no connection between meat and cancer or even a protective effect of meat on colon cancer risk. These neutral and protective studies were specifically mentioned within the studies cited by the WHO (which makes one wonder whether the WHO committee members actually read the studies referenced in its own report).
  2. The WHO relied heavily on dozens of “epidemiological” studies (which by their very nature are incapable of demonstrating a cause and effect relationship between meat and cancer) to support its claim that meat causes cancer.
  3. The WHO cited a mere SIX experimental studies suggesting a possible link between meat and colorectal cancer, four of which were conducted by the same research group.
  4. THREE of the six experimental studies were conducted solely on RATS. Rats are not humans and may not be physiologically adapted to high-meat diets. All rats were injected with powerful carcinogenic chemicals prior to being fed meat. Yes, you read that correctly.
  5. Only THREE of the six experimental studies were human studies. All were conducted with a very small number of subjects and were seriously flawed in more than one important way. Examples of flaws include using unreliable or outdated biomarkers and/or failing to include proper controls.
  6. Some of the theories put forth by the WHO about how red/processed meat might cause cancer are controversial or have already been disproved. These theories were discredited within the texts of the very same studies cited to support the WHO’s anti-meat conclusions, again suggesting that the WHO committee members either didn’t read these studies or deliberately omitted information that didn’t support the WHO’s anti-meat position.

Does it matter whether the WHO gets it right or wrong about meat and cancer? YES.

“Strong media coverage and ambiguous research results could stimulate consumers to adapt a ‘safety first’ strategy that could result in abolishment of red meat from the diet completely. However, there are reasons to keep red meat in the diet. Red meat (beef in particular) is a nutrient dense food and typically has a better ratio of N6:N3-polyunsaturated fatty acids and significantly more vitamin A, B6 and B12, zinc and iron than white meat(compared values from the Dutch Food Composition Database 2013, raw meat). Iron deficiencies are still common in parts of the populations in both developing and industrialized countries, particularly pre-school children and women of childbearing age (WHO)… Red meat also contains high levels of carnitine, coenzyme Q10, and creatine, which are bioactive compounds that may have positive effects on health.” 2)

The bottom line is that there is no good evidence that unprocessed red meat increases our risk for cancer. Fresh red meat is a highly nutritious food which has formed the foundation of human diets for nearly two million years. Red meat is a concentrated source of easily digestible, highly bioavailable protein, essential vitamins and minerals. These nutrients are more difficult to obtain from plant sources.

It makes no sense to blame an ancient, natural, whole food for the skyrocketing rates of cancer in modern times. I’m not interested in defending the reputation of processed meat (or processed foods of any kind, for that matter), but even the science behind processed meat and cancer is unconvincing, as I think you’ll agree. […]

Regardless, even if you believe in the (non-existent) power of epidemiological studies to provide meaningful information about nutrition, more than half of the 29 epidemiological studies did NOT support the WHO’s stance on unprocessed red meat and colorectal cancer.

It is irresponsible and misleading to include this random collection of positive and negative epidemiological studies as evidence against meat.

The following quote is taken from one of the experimental studies cited by the WHO. The authors of the study begin their paper with this striking statement:

“In puzzling contrast with epidemiological studies, experimental studies do not support the hypothesis that red meat increases colorectal cancer risk. Among the 12 rodent studies reported in the literature, none demonstrated a specific promotional effect of red meat.” 3)

[Oddly enough, none of these twelve “red meat is fine” studies, which the authors went on to list and describe within the text of the introduction to this article, were included in the WHO report].

I cannot emphasize enough how common it is to see statements like this in scientific papers about red meat. Over and over again, researchers see that epidemiology suggests a theoretical connection between some food and some health problem, so they conduct experiments to test the theory and find no connection. This is why our nutrition headlines are constantly changing. One day eggs are bad for you, the next day they’re fine. Epidemiologists are forever sending well-intentioned scientists on time-consuming, expensive wild goose chases, trying to prove that meat is dangerous, when all other sources–from anthropology to physiology to biochemistry to common sense—tell us that meat is nutritious and safe.

* * *

Below good discussion between Dr. Steven Gundry and Dr. Paul Saladino. It’s an uncommon dialogue. Even though Gundry is known for warning against the harmful substances in plant foods, he has shifted toward a plant-based diet in also warning against too much animal foods or at least too much protein, another issue about IGF1 not relevant to this post. As for Saladino, he is a carnivore and so takes Gundry’s argument against plants to a whole other level. Saladino sees no problem with meat, of course. And his view contradicts what Gundry writes about in his most recent book, The Longevity Paradox.

Anyway, they got onto the topic of TMAO. Saladino points out that fish has more fully formed TMAO than red meat produces in combination with grain-loving Prevotella. Even vegetables produce TMAO. So, why is beef being scapegoated? It’s pure ignorant idiocy. To further this point, Saladino explained that he has tested the microbiome of patients of his on the carnivore diet and it comes up low on the Prevotella bacteria. He doesn’t think TMAO is the danger people claim it is. But even if it were, the single safest diet might be the carnivore diet.

Gundry didn’t even disagree. He pointed out that he did testing on patients of his who are long-term vegans and now in their 70s. They had extremely high levels of TMAO. He sent their lab results to the Cleveland Clinic for an opinion. The experts there refused to believe that it was possible and so dismissed the evidence. That is the power of dietary ideology when it forms a self-enclosed reality tunnel. Red meat is bad and vegetables are good. The story changes over time. It’s the saturated fat. No, it’s the TMAO. Then it will be something else. Always looking for a rationalization to uphold the preferred dogma.

* * *

7/25/19 – Additional thoughts: There is always new research coming out. And as is typical, it is often contradictory. It is hard to know what is being studied exactly.The most basic understanding in mainstream nutrition right now seems to be that red meat is associated with TMAO by way of carnitine and Prevotella (Studies reveal role of red meat in gut bacteria, heart disease development). But there are many assumptions being made. This research tends to be epidemiological/observational and so most factors aren’t being controlled.

Worse still, they aren’t comparing the equivalent extremes, such as veganism vs carnivory but veganism and vegetarianism vs omnivory. That is to leave out the even greater complicating factor that, as the data shows, a significant number of vegans and vegetarians occasionally eat animal foods. There really aren’t that many long-term vegans and vegetarians to study because 80% of people who start the diet quit it, and of that 20% few are consistent.

As for omnivores, they are a diverse group that could include hundreds of dietary variations. One variety of omnivory is the paleo diet, slightly restricted omnivory in that grains are excluded, often along with legumes, white potatoes, dairy, added sugar, etc. The paleo diet was studied and showed higher levels of TMAO and, rather than cancer, the focus was on cardiovascular disease (Heart disease biomarker linked to paleo diet).

So, that must mean the paleo diet is bad, right? When people think of the paleo diet, they think of a caveman lugging a big hunk of meat. But the reality is that the standard paleo diet, although including red meat, emphasizes fish and heaping platefuls of vegetables. Why is red meat getting blamed? In a bizarre twist, the lead researcher of the paleo study, Dr. Angela Genoni, thought the problem was the lack of grains. But it precisely grains that the TMAO-producing Prevotella gut bacteria love so much. How could reducing grains increase TMAO? No explanation was offered. Before we praise grains, why not look at the sub-population of vegans, vegetarians, fruitivores, etc who also avoid grains?

There is a more rational and probable factor. It turns out that fish and vegetables raise TMAO levels higher than red meat (Eat your vegetables (and fish): Another reason why they may promote heart health). This solves the mystery of why some Dr. Gundry’s vegan patients had high TMAO levels. Yet, in another bizarre leap of logic, the same TMAO that is used to castigate red meat suddenly is portrayed as healthy in reducing cardiovascular risk when it comes from sources other than red meat. It is the presence of red meat that somehow magically transforms TMAO into an evil substance that will kill you. Or maybe, just maybe it has nothing directly to do with TMAO alone.

After a long and detailed analysis of the evidence, Dr. Georgia Ede concluded that, “As far as I can tell, the authors’ theory that red meat provides carnitine for bacteria to transform into TMA which our liver then converts to TMAO, which causes our macrophages to fill up with cholesterol, block our arteries, and cause heart attacks is just that–a theory–full of sound and fury, signifying nothing” (Does Carnitine from Red Meat Cause Heart Disease?).